Lean Mass - Start
Lean Mass - Start Original price was: 270,00 €.Current price is: 230,00 €.
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Repair Matrix - Start
Repair Matrix - Start Original price was: 186,00 €.Current price is: 158,00 €.

Lean Mass – Advanced

The Lean Mass – Advanced expands the Start protocol to six complementary compounds: HGH (Somatropin), IGF-1 LR3, PEG-MGF, the BPC-157 + TB-500 repair pair, the mitochondrial peptide MOTS-c and master-antioxidant Glutathione.

Built for deeper research into the growth-hormone / IGF-1 axis, muscle repair, mitochondrial output and recovery resilience – a complete bundled set at a single discounted price.

Original price was: 482,00 €.Current price is: 362,00 €.

The expanded 6-part anabolic protocol: HGH, IGF-1 LR3, PEG-MGF, BPC-157 + TB-500, MOTS-c and Glutathione.

Direct Anabolic Signaling
via IGF-1 LR3 receptor

Description

Mechanism of Action​

The Lean Mass – Advanced bundle is designed for comprehensive investigation into anabolic and recovery pathways. HGH (Somatropin) is studied as the upstream driver of the growth-hormone / IGF-1 axis, complemented by IGF-1 LR3 for sustained receptor activation and PEG-MGF for satellite-cell proliferation. The BPC-157 + TB-500 pair is researched for angiogenesis and tissue repair, while MOTS-c contributes to mitochondrial homeostasis and Glutathione supports cellular redox balance, together offering a synergistic platform for advanced anabolic research.

Benefits

  • Direct Anabolic Signaling – IGF-1 LR3 is researched for its direct activation of the IGF-1 receptor, initiating intracellular growth cascades and promoting protein synthesis.
  • Adipose Tissue Reduction – HGH (Somatropin) is studied for stimulating lipolysis and promoting fat oxidation, contributing to improved body composition.
  • Synergistic Tissue Repair – The BPC-157 and TB-500 combination is investigated for its synergistic ability to accelerate the repair of muscle, tendon, and ligament injuries.
  • Enhanced Mitochondrial Energy – MOTS-c is researched for activating the AMPK pathway, enhancing mitochondrial respiration, and improving cellular energy balance and ATP synthesis.
  • Master Antioxidant Defense – Glutathione is studied for its critical role in neutralizing free radicals and protecting cellular structures from oxidative damage.
  • Muscle Stem Cell Activation – PEG-MGF is investigated for its ability to stimulate satellite cells, supporting early-phase muscle regeneration and structural repair following mechanical overload.
  • Accelerated Tissue Healing – HGH (Somatropin) is studied for its accelerated wound and tissue healing properties, attributed to increased collagen production and enhanced fibroblast activity.
  • Reduced Inflammatory Stress – BPC-157, TB-500, MOTS-c, and Glutathione are researched for their roles in reducing pro-inflammatory mediators and mitigating oxidative stress.

Research Data​

HGH (Somatropin)

Study/modelReported effect
Human clinical trials (GH-deficient adults)

↑ lean body mass (~3.5 kg) and ↓ fat mass (~2.0 kg) after 6 months of administration

Human clinical trials (elderly population)

↑ skin thickness and elasticity; improved collagen deposition

Animal models (fracture healing)

Accelerated callus formation and ↑ osteoblast activity

Preclinical wound healing studies

Enhanced fibroblast proliferation and collagen synthesis

Metabolic research (human)

Improved lipid profile (↓ LDL, ↑ HDL) and glucose utilization

Exercise recovery studies

Shortened muscle recovery time and increased performance capacity

In vitro studies (cell culture)

Upregulated STAT5 signaling and IGF-1 gene expression

Long-term administration models

Sustained increase in protein turnover and mitochondrial activity

IGF-1LR3

Study / ModelReported effect
Rodent skeletal muscle model↑ myofiber hypertrophy and protein synthesis via IGF-1R activation
In vitro myoblast culture↑ proliferation and differentiation; enhanced Akt/mTOR signaling
Pharmacokinetic comparison vs native IGF-1Extended half-life and reduced IGFBP binding affinity
Cellular repair models↑ satellite cell activation and tissue regeneration markers
Glucose metabolism studies↑ peripheral glucose uptake; modulated insulin sensitivity
Anabolic signaling assaysSustained receptor phosphorylation and downstream PI3K activation

PEG-MGF

Study / ModelReported effect
Rodent skeletal muscle injury model↑ Satellite cell activation and accelerated myofiber regeneration
In vitro myoblast culture↑ Proliferation and delayed differentiation, expanding the myogenic pool
Mechanical overload model (rat)↑ Local IGF-1Ec splice variant signaling and hypertrophic response
Cardiac ischemia modelReduced cardiomyocyte apoptosis and improved tissue recovery markers
Pharmacokinetic comparison (PEG-MGF vs native MGF)Extended plasma half-life from minutes to several hours
Aged murine muscle modelPartial restoration of satellite cell responsiveness to mechanical stress
In vivo denervation/atrophy model↓ Muscle protein degradation markers; preserved fiber cross-sectional area

BPC-157 + TB-500

Study/modelReported effect
Rat Achilles tendon transection

Faster collagen fiber alignment and fibroblast proliferation by day 7-10; tensile strength ~30-40% higher vs control.

Rodent medial collateral ligament injury

Improved ligament histology and biomechanical strength; reduced scar tissue density vs saline.

Skeletal muscle contusion (mouse)

Earlier myofiber regeneration with denser cross-linking and smaller necrotic zones by day 14.

Full-thickness skin wound (rodent)

↑ capillary density and re-epithelialization rate; combined use outperforms single-peptide arms.

Angiogenesis assays (preclinical)

TB-500 ↑ VEGF signaling and endothelial migration; BPC-157 stabilizes vasculature → net ↑ perfusion.

Inflammation models (cell/rodent)

↓ TNF-α, IL-6 and oxidative stress markers; pro-repair cytokine profile supports tissue remodeling.

Tendon fibroblast and ECM markers (in vitro)

↑ fibroblast migration and collagen I/III organization; improved FAK-paxillin pathway signaling.

Peripheral nerve crush (rodent)

Trends toward faster functional recovery and axonal sprouting alongside improved local perfusion.

GI mucosal injury (rodent)

BPC-157 contributes gut barrier protection; pairing with TB-500 maintains microcirculatory flow.

Overuse/strain models (rodent)

Reduced time to functional recovery and lower edema scores; supports maintenance protocols.

MOTS-c

Study/modelReported effect
Human observational studies (older adults)

↓ endogenous MOTS-c levels correlate with insulin resistance and aging

Animal models (diet-induced obesity)

↓ fat accumulation, ↑ insulin sensitivity, and restored glucose tolerance

Exercise physiology studies

↑ endurance performance and mitochondrial gene expression in muscle

Cellular stress models

↑ AMPK activation and mitochondrial ROS reduction under oxidative stress

High-fat diet mice

↓ hepatic lipid accumulation and improved metabolic parameters

In vitro myocyte cultures

↑ GLUT4 expression and glucose uptake after peptide exposure

Human pilot trial (2022)

Safe SubQ administration; improved fasting glucose and perceived energy

Longevity studies (aged mice)

↑ median lifespan and improved skeletal muscle mitochondrial function

Glutathione

Study/modelReported effect
Human trials (oral and IV administration)

↑ Plasma GSH levels, ↓ oxidative biomarkers (MDA, 8-OHdG)

Animal oxidative stress models

↓ Lipid peroxidation and improved mitochondrial GSH:GSSG ratio

Hepatotoxicity models (CCl4, acetaminophen)

↓ ALT/AST, ↓ hepatic necrosis, improved antioxidant enzyme activity

Neurodegenerative disease models

Protection of dopaminergic neurons and ↓ oxidative stress markers

In vitro melanocyte cultures

↓ Tyrosinase activity and melanin synthesis via GSH-mediated inhibition

Inflammatory models

↓ TNF-α, IL-6, and CRP, supporting immunomodulatory roles

Pharmacokinetic assessments

↑ Cellular uptake with liposomal and SubQ formulations

Stack Suggestions​

This bundle is suited for researchers investigating the growth-hormone / IGF-1 axis, muscle hypertrophy and recovery resilience in advanced research models, providing a robust framework spanning anabolic signaling, tissue repair and mitochondrial support.

Pen Dosage Chart​

HGH (Somatropin)

HGH Somatropin Pen 24 IU
Volume2.0 mL
mg/mL12 IU/mL
Click-to-Dose1 click = 0.12 IU
Example(s)8 clicks = 0.96 IU
HGH Somatropin Pen 36 IU
Volume3.0 mL
mg/mL12 IU/mL
Click-to-Dose1 click = 0.12 IU
Example(s)8 clicks = 0.96 IU

IGF-1LR3

IGF-1LR3 Pen 1 mg
Volume1 mL
mg/mL1 mg/mL
Click-to-Dose1 click = 0.01 mg
Example(s)10 clicks = 0.1 mg

PEG-MGF

PEG-MGF Pen 5 mg
Volume2 mL
mg/mL2.5 mg/mL
Click-to-Dose1 click = 0.025 mg
Example(s)10 clicks = 0.25 mg

BPC-157 + TB-500

BPC-157 + TB-500 Pen 5 + 5 mg
Volume2.0 mL
mg/mL5 mg/mL
Click-to-Dose1 click = 0.05 mg
Example(s)10 clicks = 0.5 mg; 50 clicks = 2.5 mg
BPC-157 + TB-500 Pen 10 + 10 mg
Volume2.0 mL
mg/mL10 mg/mL
Click-to-Dose1 click = 0.10 mg
Example(s)10 clicks = 1 mg; 25 clicks = 2.5 mg

MOTS-c

MOTS-c Pen 10 mg
Volume2.0 mL
mg/mL5 mg/mL
Click-to-Dose1 click = 0.05 mg
Example(s)20 clicks = 1 mg

Glutathione

Glutathione Pen 1500 mg
Volume3 mL
mg/mL500 mg/mL
Click-to-Dose1 click = 5 mg
Example(s)10 clicks = 50 mg

Dosage & Protocols Variations​

HGH (Somatropin)

Standard Research Protocol

  • Dose: 1 – 2 IU (= 8–17 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: 1× daily
  • Cycle Interval: 4 week rest
  • Goal / Description: Commonly used for studying anabolic and metabolic regulation

High-Intensity Regeneration

  • Dose: 3 – 5 IU (= 25–42 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: 1× daily
  • Cycle Interval: 8 week rest
  • Goal / Description: Used in experimental designs focused on tissue and recovery response

Pulsed Night Protocol

  • Dose: 1.5 – 2.5 IU (= 13–21 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: Every Other Day
  • Cycle Interval: 4 week rest
  • Goal / Description: Mimics physiological nocturnal GH release cycles

IGF-1LR3

Standard Research Protocol

  • Dose: 0.02 – 0.05 mg (= 2–5 clicks)
  • Duration: 4 – 6 weeks
  • Frequency: Daily
  • Cycle Interval: 4 weeks off before repeating
  • Goal / Description: Baseline anabolic signaling and muscle growth models.

Therapeutic Research Protocol

  • Dose: 0.05 – 0.1 mg (= 5–10 clicks)
  • Duration: 4 weeks
  • Frequency: Daily, post-training in targeted muscle groups
  • Cycle Interval: 4 – 6 weeks off before repeating
  • Goal / Description: Higher-dose protocol for hypertrophy and cellular repair studies.

Stacked Protocol (IGF-1 LR3 + CJC-1295/Ipamorelin)

  • Dose: 0.02 – 0.04 mg IGF-1 LR3 (= 2–4 clicks)
  • Duration: 4 – 6 weeks
  • Frequency: Daily
  • Cycle Interval: 4 weeks off before repeating
  • Goal / Description: Combined GH and IGF-1 axis stimulation for anabolic research.

PEG-MGF

Standard Research Protocol

  • Dose: 0.2 – 0.4 mg (= 8–16 clicks)
  • Duration: 4 – 6 weeks
  • Frequency: 2 – 3× per week
  • Cycle Interval: 4 weeks off before repeating
  • Goal / Description: Baseline protocol for muscle regeneration and satellite cell activation models.

Therapeutic Research Protocol

  • Dose: 0.4 – 0.6 mg (= 16–24 clicks)
  • Duration: 6 – 8 weeks
  • Frequency: 3× per week post-training
  • Cycle Interval: 4 – 6 weeks off before repeating
  • Goal / Description: Higher-dose schedule used in hypertrophy and localized repair research.

Biohacker Protocol (experimental)

  • Dose: 0.1 – 0.2 mg (= 4–8 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: 2× per week
  • Cycle Interval: 2 – 4 weeks off before repeating
  • Goal / Description: Lower-dose continuous design exploring sustained anabolic signaling.

BPC-157 + TB-500

Standard Research Protocol

  • Dose: 0.5 – 1 mg (variant 5 + 5 mg pen = 10–20 clicks / variant 10 + 10 mg pen = 5–10 clicks)
  • Duration: 4 – 6 weeks
  • Frequency: 1× daily
  • Cycle Interval: 4 week rest
  • Goal / Description: Basic tissue recovery support model

Enhanced Regeneration Protocol

  • Dose: 1 – 1.5 mg (variant 5 + 5 mg pen = 20–30 clicks / variant 10 + 10 mg pen = 10–15 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: Every other day
  • Cycle Interval: 4 week rest
  • Goal / Description: Designed for extended regenerative studies, emphasizing vascular and muscular adaptation

Post-Load Model

  • Dose: 2 mg (variant 5 + 5 mg pen = 40 clicks / variant 10 + 10 mg pen = 20 clicks)
  • Duration: 2 – 4 weeks
  • Frequency: 1× daily
  • Cycle Interval: 2 week rest
  • Goal / Description: Applied in post-strain or high-load experimental recovery

Biohacker Protocol

  • Dose: 0.5 mg (variant 5 + 5 mg pen = 10 clicks / variant 10 + 10 mg pen = 5 clicks)
  • Duration: Continuous
  • Frequency: 5× weekly
  • Cycle Interval: 2 week rest
  • Goal / Description: Experimental long-term maintenance design emphasizing consistent angiogenic response

MOTS-c

Standard Metabolic Protocol

  • Dose: 0.5 – 1 mg (= 10–20 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: 1× daily
  • Cycle Interval:  4-week rest
  • Goal / Description: Commonly used for metabolic regulation and insulin sensitivity studies

Performance & Endurance Protocol

  • Dose: 1 mg (= 20 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: Every Other Day
  • Cycle Interval: 4-week rest
  • Goal / Description: Applied in models focused on energy optimization and fatigue resistance

Mitochondrial Recovery Protocol

  • Dose: 5 mg (= 100 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: 1× daily
  • Cycle Interval: 8-week rest
  • Goal / Description: Studied for mitochondrial repair and oxidative stress response

Glutathione

Standard Antioxidant Protocol

  • Dose: 200 – 400 mg (= 40–80 clicks)
  • Duration: 4 – 8 weeks
  • Frequency: 3× weekly
  • Cycle Interval: 4-week rest
  • Goal / Description: ↑ Systemic antioxidant capacity, baseline redox support

Intensive Detoxification Protocol

  • Dose: 500 – 600 mg (= 100–120 clicks)
  • Duration: 4 weeks
  • Frequency: 5× weekly
  • Cycle Interval: 8-week rest
  • Goal / Description: Rapid ↑ GSH levels for detoxification models, tissue saturation

Maintenance Protocol

  • Dose: 150 mg (= 30 clicks)
  • Duration: 8 – 12 weeks
  • Frequency: 3× weekly
  • Cycle Interval: 8-week rest
  • Goal / Description: Long-term maintenance of improved GSH status

Possible Side Effects​

This bundle combines multiple research compounds; the per-compound safety notes below apply. For laboratory research use only – not for human consumption.

HGH (Somatropin)

HGH, as a research hormone promoting growth, may induce various side effects in experimental models, primarily related to fluid and metabolic shifts. These are dose-dependent and prominent at higher levels. Monitoring is crucial for subcutaneous administration.

Peripheral Edema: Commonly observed as swelling in limbs, due to sodium retention via IGF-1. It subsides with adaptation or dose reduction.

Joint Pain and Arthralgias: Mild discomfort in joints, linked to rapid tissue growth and cartilage changes. Frequency decreases in slower protocols.

Carpal Tunnel Syndrome: Nerve compression symptoms like tingling, attributed to soft tissue expansion. Resolves post-treatment.

Headache: Transient, possibly from intracranial pressure or vascular effects.

Insulin Resistance: Altered glucose tolerance, with potential hyperglycemia in models. Managed by monitoring.

Fatigue: Early lethargy from metabolic adjustments.

Most side effects are transient and manageable through adjustments. Prolonged use warrants vigilance for acromegaly-like changes or cardiovascular strain, though rare in controlled settings.

IGF-1LR3

IGF-1 LR3 is generally tolerated in research models, but several effects have been reported in experimental and observational data:

  • Hypoglycemia due to insulin-like activity on glucose uptake.
  • Localized swelling, redness, or discomfort at injection site.
  • Transient headaches or lightheadedness during initial dosing.
  • Joint pain or muscle cramps in prolonged research protocols.
  • Potential organ enlargement with extended high-dose exposure in animal models.

No evidence of acute toxicity has been observed at standard research doses, though long-term effects on cellular proliferation remain under investigation.

PEG-MGF

PEG-MGF is generally well-tolerated in preclinical research and limited experimental human observations.

Reported side effects are uncommon and typically mild:

  • Localized redness, swelling, or irritation at the injection site.
  • Transient hypoglycemia-like symptoms due to IGF-1 pathway activation.
  • Mild fatigue or lethargy shortly after administration.
  • Occasional headache or lightheadedness in sensitive subjects.
  • Possible localized muscle tightness near the injection area.

No evidence of severe hormonal, cardiovascular, or hepatic adverse effects has been observed in available research data. Long-term safety profiles remain under investigation, particularly regarding sustained IGF-1 receptor activation and tissue-specific growth signaling.

BPC-157 + TB-500

The BPC-157 & TB-500 blend, as research peptides involved in regeneration, may elicit side effects in experimental models, mainly at injection sites or systemically. Effects are typically mild and dose-related, with subcutaneous administration sometimes causing local responses. Close monitoring is essential.

Injection Site Reactions: Common observations include redness, swelling, or pain at the site, resolving within days. Rotating areas and proper technique minimize this.

Nausea or Gastrointestinal Upset: Mild queasiness may occur, linked to BPC-157’s gastric origins, especially at higher doses. It subsides with adaptation.

Fatigue or Dizziness: Transient lethargy has been noted early on, possibly from metabolic shifts or inflammation reduction. This resolves as models stabilize.

Headache: Occasional mild headaches, attributed to vascular changes from angiogenesis promotion.

Most side effects are transient and manageable via dose adjustment in research. Limited data suggest vigilance for potential long-term effects like overgrowth, though rare in controlled animal studies.

MOTS-c

MOTS-c, as a research peptide regulating metabolism, may induce various side effects in experimental models, primarily related to its influence on energy systems. These effects are often dose-dependent and more prominent during initial administration. It’s crucial to monitor subjects closely, as subcutaneous delivery can sometimes cause localized reactions.

Injection Site Reactions: Commonly observed, manifesting as redness or swelling that resolves within hours. Rotating sites minimizes this.
Fatigue: A sense of lethargy reported early on, possibly due to metabolic shifts. It often resolves as homeostasis stabilizes.
Nausea: Mild gastrointestinal upset, linked to AMPK activation. Typically transient.
Headache: Occasional, attributed to vascular adjustments.

Most side effects are transient and manageable through dose adjustments in research settings. However, prolonged exposure warrants vigilance for potential hypersensitivity, though rare in controlled protocols.

Glutathione

Glutathione supplementation is generally well-tolerated due to its endogenous nature, but some individuals may experience side effects, particularly with higher doses or sensitive constitutions. The most common adverse reactions are related to gastrointestinal adjustments and administration site responses with subcutaneous injection protocols.

Gastrointestinal Effects: Mild nausea, abdominal cramping, bloating, and flatulence may occur, especially during the initial supplementation period. These symptoms typically resolve as the body adapts to increased glutathione levels. Some users report a metallic or sulfur-like taste, which is attributed to the cysteine component of the molecule.

Injection Site Reactions: With subcutaneous administration, mild redness, swelling, or irritation at the injection site may occur. These reactions are typically transient and resolve within 24-48 hours. Proper injection technique and site rotation can minimize these effects.

Allergic Reactions: Although rare, some individuals may experience allergic responses including skin rashes, hives, or in severe cases, difficulty breathing. Those with known sensitivities to sulfur-containing compounds should exercise particular caution.

Respiratory Considerations: Individuals with asthma or respiratory sensitivities should avoid inhaled forms, as glutathione may trigger bronchospasms or respiratory distress in predisposed individuals.

Headaches and Fatigue: Some users report mild headaches or temporary fatigue during initial supplementation, likely related to detoxification processes and cellular adjustments to enhanced antioxidant capacity.

It is important to note that most side effects are mild, transient, and resolve with continued use or dosage adjustment. However, individuals should discontinue use and consult healthcare providers if adverse reactions persist or worsen.

Product Attributes​

Scientific References​

HGH (Somatropin)

IGF-1LR3

PEG-MGF

BPC-157 + TB-500

MOTS-c

Glutathione

Included In The Box

Every product arrives in a premium, custom-designed PEPTIDE.Power box, engineered for convenience, hygiene, and safe storage in your refrigerator. Inside, you will find everything needed for your full research protocol:

  • 1× Disposable Pre-Mixed Injection Pen
  • Powered by our proprietary PSM Technology™ – precision stabilization & mixing system for consistent potency
  • 10× Ultra-thin Needles (33G, 4 mm)
  • 10× Alcohol Pads for sterile preparation
  • Internal Stabilizing Foam Insert to prevent shaking during transport
  • Instruction Panel printed on the inside of the box for quick reference
  • Security Seal Sticker ensuring the package has not been opened or tampered with

Store the product in a refrigerator at 1 – 8°C immediately upon delivery. To maintain optimal stability, keep the pen away from light, and do not expose it to repeated temperature changes.

Once reconstituted (all our pens come pre-mixed), research compounds remain stable for 6 – 8 weeks under proper refrigeration.

Do not freeze after reconstitution. Always keep the box closed so the pen, needles, and alcohol pads stay clean and protected.

For best results, use the product consistently within the recommended time window and always follow your research protocol.

We ship with Next-Day EU Delivery via DHL Express or UPS Express.

All orders are prepared fresh on the day of dispatch, placed in EPS Cold-Chain Transport Boxes, and shipped with cooling elements to maintain a stable temperature throughout the journey.

Our logistics process is designed so the package arrives overnight, avoiding customs delays inside the European Union.

Products are shipped from our EU facility, ensuring no import duties, no customs clearance, and always fast and secure delivery.

Due to the nature of research peptides and the high-risk category assigned by payment processors, credit card companies do not generally support merchants in this field.

For this reason, we accept mainly Bank Transfers.

We also work with a crypto payment provider, and from time to time, card payments may be available depending on processor availability.

Within the European Union, SEPA transfers are fast, low-cost, and usually arrive within minutes to a few hours, making the payment process smooth and simple.

Once the transfer is received, your order is prepared immediately and dispatched the same day, depending on the daily cut-off time.

Please note that we do not dispatch shipments on Fridays or on days before official public holidays. This is done to ensure that parcels can be delivered on the next working day and are not held in transit over weekends or holidays.

This method ensures compliance, security, and continuity of service for all customers across the EU.

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