Sleep – Start
The Sleep Start stack combines DSIP, Selank and Epithalon — three peptides studied in the context of sleep architecture, relaxation and circadian rhythm — into one curated research kit.
Each component is supplied at research-grade purity for laboratory work. For research purposes only; not for human consumption.
Prețul inițial a fost: 212,00 €.180,00 €Prețul curent este: 180,00 €.
Un kit de cercetare axat pe somn, cu DSIP, Selank și Epithalon pentru studii circadiene și de recuperare.
Ce include acest pachet
Sleep - Start - Exploring Foundational Sleep Regulation Research
DSIP for delta sleep studies.
Selank's anxiolytic properties.
Epithalon's pineal gland influence.
Selank for neuronal health.
DSIP's role in sleep stages.
Epithalon supports natural cycles.
Selank for anxiety research.
Stack for comprehensive sleep research.
Description
Mechanism of Action
This research stack combines compounds known for distinct yet complementary roles in sleep regulation studies. DSIP is investigated for its potential to induce delta sleep. Selank is explored for anxiolytic and neuroprotective properties, indirectly supporting sleep quality via stress modulation. Epithalon is researched for its influence on the pineal gland and circadian rhythms, contributing to sleep-wake cycle regulation.
Benefits
- Delta Wave Induction – DSIP research for deep sleep.
- Stress Modulation – Selank for anxiolytic research.
- Circadian Rhythm Support – Epithalon’s pineal gland research.
- Neuroprotection Studies – Selank’s cognitive research.
- Sleep Cycle Regulation – Epithalon’s broad influence.
- Sleep Onset Research – DSIP’s role in initiation.
Research Data
DSIP
| Study / Model | Reported effect |
|---|---|
| Rodent EEG sleep studies | ↑ delta-wave activity and improved slow-wave sleep continuity |
| Stress-induced animal models | ↓ corticosteroid release and attenuated HPA-axis hyperactivity |
| Chronic insomnia observational research | Improved subjective sleep onset and reduced nocturnal awakenings |
| Opioid withdrawal clinical observations | ↓ withdrawal severity and improved autonomic stabilization |
| Oxidative stress in vitro assays | ↓ lipid peroxidation markers; antioxidant enzyme modulation |
| Neuroendocrine animal studies | Modulation of GH, LH, and somatostatin secretion patterns |
| Pain perception rodent models | Elevated nociceptive thresholds and analgesic-like response |
Selank
| Study / Model | Reported effect |
|---|---|
| Generalized anxiety disorder clinical trials | ↓ anxiety scores comparable to medazepam without sedation or withdrawal |
| Rat elevated plus-maze model | ↓ anxiety-like behavior; ↑ open-arm exploration time |
| Cortical neurotransmitter analysis (rodent) | Normalized GABA turnover; ↑ serotonin and dopamine metabolism |
| BDNF expression studies in hippocampus | ↑ BDNF mRNA expression supporting neuroplasticity |
| Stress-induced immunosuppression models | Restored interferon and cytokine balance; ↑ immune resilience |
| Cognitive performance tasks in healthy volunteers | ↑ attention, memory consolidation, and mental endurance |
| Enkephalin degradation assays | Inhibition of enkephalin breakdown; prolonged endogenous opioid activity |
Epithalon
| Study / Model | Reported effect |
|---|---|
| Human somatic cell culture | ↑ Telomerase activity, ↑ telomere length in dividing cells |
| Aged mice longevity studies | Extended median lifespan, ↓ age-related tumor incidence |
| Pineal gland animal models | Restored melatonin secretion rhythm, normalized circadian markers |
| Elderly human observational cohort | Improved sleep architecture, ↑ nocturnal melatonin levels |
| Retinal degeneration rat model | ↓ Photoreceptor loss, preserved retinal pigment epithelium |
| Oxidative stress in vitro assays | ↓ Lipid peroxidation, ↑ antioxidant enzyme expression |
| Immunosenescence rodent studies | Restored T-cell function, normalized thymic activity |
Stack Suggestions
This research bundle is ideal for investigators initiating studies into fundamental sleep mechanisms. It provides a foundational set of compounds to explore various facets of sleep induction, quality, and circadian rhythm regulation in a research setting.
Pen Dosage Chart
DSIP
| DSIP Pen 5 mg | |
|---|---|
| Volume | 2.0 mL (after reconstitution) |
| mg/mL | 2.5 mg/mL |
| Click-to-Dose | 1 click = 0.025 mg |
| Example(s) | 40 clicks = 1 mg; 80 clicks = 2 mg |
Selank
| Selank Pen 10 mg | |
|---|---|
| Volume | 2.0 mL (after reconstitution) |
| mg/mL | 5.0 mg/mL |
| Click-to-Dose | 1 click = 0.05 mg |
| Example(s) | 30 clicks = 1.5 mg; 60 clicks = 3 mg |
Epithalon
| Epithalon Pen 20 mg | |
|---|---|
| Volume | 2 mL |
| mg/mL | 10 mg/mL |
| Click-to-Dose | 1 click = 0.1 mg |
| Example(s) | 10 clicks = 1 mg |
Dosage & Protocols Variations
DSIP
Standard Research Protocol
- Dose: 0.1 – 0.3 mg (= 4–12 clicks)
- Duration: 2 – 4 weeks
- Frequency: Once daily, prior to rest phase
- Cycle Interval: 2 weeks off before repeating
- Goal / Description: Baseline protocol used in sleep architecture and circadian rhythm research models.
Therapeutic Research Protocol
- Dose: 0.3 – 0.5 mg (= 12–20 clicks)
- Duration: 3 – 5 weeks
- Frequency: Daily, evening administration
- Cycle Interval: 3 – 4 weeks off before repeating
- Goal / Description: Higher-dose model for stress-response and neuroendocrine regulation studies.
Biohacker Protocol (experimental)
- Dose: 0.05 – 0.1 mg (= 2–4 clicks)
- Duration: 4 – 6 weeks
- Frequency: Daily microdose before rest cycle
- Cycle Interval: 1 – 2 weeks off before repeating
- Goal / Description: Low-dose continuous exploration of sleep quality and recovery markers.
Selank
Standard Research Protocol
- Dose: 0.25 – 0.5 mg (= 5–10 clicks)
- Duration: 2 – 3 weeks
- Frequency: Daily (SubQ)
- Cycle Interval: 2 – 4 weeks off before repeating
- Goal / Description: Baseline protocol for anxiolytic and cognitive stability models.
Therapeutic Research Protocol
- Dose: 0.5 – 0.9 mg (= 10–18 clicks)
- Duration: 3 – 4 weeks
- Frequency: 2× daily, divided doses
- Cycle Interval: 4 weeks off before repeating
- Goal / Description: Higher-dose protocol used in stress-response and GABAergic modulation studies.
Biohacker Protocol (experimental)
- Dose: 0.1 – 0.2 mg (= 2–4 clicks)
- Duration: 4 – 6 weeks
- Frequency: Daily microdose
- Cycle Interval: 2 weeks off before repeating
- Goal / Description: Low-dose continuous exposure for cognitive and mood-balance research.
Stacked Protocol (Selank + Semax)
- Dose: 0.3 mg Selank + 0.3 mg Semax (= 6 clicks)
- Duration: 2 – 3 weeks
- Frequency: Daily
- Cycle Interval: 3 – 4 weeks off before repeating
- Goal / Description: Combined neuropeptide protocol for cognitive and anxiolytic research models.
Epithalon
Standard Research Protocol
- Dose: 5 – 10 mg (= 50–100 clicks)
- Duration: 2 – 3 weeks
- Frequency: Daily
- Cycle Interval: 4 – 6 months off before repeating
- Goal / Description: Baseline protocol used in telomerase activation and cellular aging models.
Therapeutic Research Protocol
- Dose: 10 – 20 mg (= 100–200 clicks)
- Duration: 10 – 20 days
- Frequency: Daily or split into two administrations
- Cycle Interval: 3 – 6 months off before repeating
- Goal / Description: Higher-dose schedule explored in longevity and pineal signaling research.
Biohacker Protocol (experimental)
- Dose: 2 – 5 mg (= 20–50 clicks)
- Duration: 4 – 6 weeks
- Frequency: 5 days per week
- Cycle Interval: 2 – 3 months off before repeating
- Goal / Description: Microdose continuous approach in experimental aging models.
Possible Side Effects
DSIP
DSIP is generally well-tolerated in animal and limited human research studies.
Reported side effects are infrequent and mild:
- Mild headache or dizziness following administration.
- Transient drowsiness or grogginess upon waking.
- Localized irritation at the injection site.
- Occasional changes in dream intensity or vividness.
No evidence of hormonal, hepatic, or cardiovascular adverse effects has been observed in available data.
Selank
Selank is generally well-tolerated in animal and limited human clinical studies, with no significant adverse effects reported at standard research doses.
Reported observations include:
- Mild transient drowsiness or fatigue during initial dosing.
- Occasional headache or lightheadedness in sensitive subjects.
- Localized irritation or redness at the injection site.
- Rare reports of mild nasal discomfort with intranasal administration.
Unlike classical anxiolytics, Selank has not been observed to produce sedation, dependence, withdrawal, or cognitive impairment in available research data. No evidence of hormonal, hepatic, or cardiovascular adverse effects has been documented.
Epithalon
Epithalon is generally well-tolerated in preclinical and limited human observational studies.
Reported side effects are rare and typically mild:
- Transient drowsiness or mild fatigue following administration.
- Localized irritation, redness, or tenderness at injection site.
- Occasional mild headache during initial dosing periods.
- Temporary changes in sleep patterns linked to pineal signaling modulation.
No evidence of hormonal, hepatic, or systemic adverse effects has been observed in available research data.
Product Attributes
Scientific References
DSIP
- Delta sleep-inducing peptide (DSIP): a review Observational | Animal | In vitro
- Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients Human RCT | Observational
- The delta sleep-inducing peptide (DSIP): a still unresolved riddle Animal | In vitro
- DSIP in the treatment of chronic insomnia: a double-blind clinical trial Human RCT
- Influence of DSIP on the secretion of pituitary hormones in humans Observational | Human RCT
- Delta sleep-inducing peptide modulates the stress response in rats Animal
- Delta sleep-inducing peptide: structure, function and clinical perspectives Observational | Animal | In vitro
- Antioxidant properties of delta sleep-inducing peptide in experimental models Animal | In vitro
Selank
- Anxiolytic activity of the heptapeptide Selank in clinical trials Human RCT | Observational
- Effects of Selank on the expression of genes encoding inflammatory factors and BDNF Animal | In vitro
- Selank enhances the expression of BDNF and the trkB receptor in the hippocampus Animal
- Comparative study of the anxiolytic effects of Selank and medazepam in patients with generalized anxiety disorder Human RCT
- Effect of Selank on monoamine neurotransmitter metabolism in the brain of rats Animal
- Selank and its analogs modulate GABAergic transmission in experimental anxiety models Animal | In vitro
- Peptide Selank as a candidate for the correction of cognitive deficits Animal
- Immunomodulatory and anxiolytic properties of the synthetic peptide Selank Observational | Animal
Epithalon
- Peptide promotes overcoming of the division limit in human somatic cell In vitro
- Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells In vitro
- Inhibition of development of spontaneous mammary tumors in mice by Epithalon Animal
- Effect of Epithalon on biomarkers of aging, life span and spontaneous tumor incidence in female rats Animal
- Pineal peptide preparation Epithalamin and tetrapeptide Epitalon: results of clinical use in humans Observational
- Peptides and aging: relevance to cancer prevention and longevity research Animal | In vitro
- Epithalon and aging: experimental and clinical perspectives Observational | Animal
- Telomerase activation and senescence pathways in peptide research In vitro
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