Epithalon - Telomerase Activation & Cellular Aging
Description
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from research on epithalamin, a pineal gland extract studied in aging biology. The peptide has been investigated for its potential ability to activate telomerase, the enzyme responsible for maintaining telomere length. Telomeres are protective caps at the ends of chromosomes that shorten during cellular replication.
In preclinical and regional human studies, Epithalon has been examined for its influence on telomere dynamics, pineal function, and age-associated cellular markers. Research domains include cellular senescence, circadian regulation, and longevity-focused molecular investigations.
Clinical Status
Human RCT ▣ | Observational ▣ | Animal ✔ | In vitro ✔
Primarily studied in preclinical and regional aging research contexts, with limited exploratory human data.
Mechanism of Action
Epithalon is studied for its potential to activate telomerase, an enzyme that helps maintain telomere length in dividing cells. By influencing telomere biology, it is explored in research focused on cellular aging and genomic stability.
Benefits
- Investigated for telomerase activation and telomere maintenance:
Telomeres shorten progressively with each cell division, eventually contributing to replicative senescence. Epithalon has been studied for its potential to increase telomerase activity, the enzyme responsible for extending telomeric DNA sequences. In laboratory models, activation of telomerase is associated with delayed cellular aging markers. By influencing this enzymatic pathway, Epithalon is positioned within telomere biology research. - Supports genomic stability research:
Telomere shortening can lead to chromosomal instability and altered gene expression. Maintaining telomere length is associated with preservation of genomic integrity in experimental systems. Epithalon is explored for its influence on chromosomal end protection mechanisms, contributing to investigation of cellular stability pathways. - Engages cellular senescence pathways:
Cellular senescence is characterized by growth arrest and altered gene expression. Telomerase modulation may influence the timing of senescence onset in dividing cells. Epithalon is studied within models examining how telomere dynamics interact with aging-associated signaling networks. - Influences pineal gland and circadian regulation research:
Epithalon originates from research on epithalamin, associated with pineal gland activity. The pineal gland regulates melatonin secretion and circadian rhythms. Modulation of pineal-related signaling pathways connects Epithalon to neuroendocrine aging research domains. - Examined in oxidative stress response models:
Oxidative stress contributes to telomere shortening and cellular damage. Experimental systems investigating Epithalon often evaluate oxidative stress markers alongside telomere dynamics. This positions the peptide within broader cellular resilience research frameworks. - Studied in replicative lifespan models:
By influencing telomerase activity, Epithalon has been examined in cellular models assessing replicative potential. Increased replicative capacity is linked to extended cellular lifespan in controlled laboratory conditions. These findings support its inclusion in experimental longevity research discussions. - Targets aging biology at the chromosomal level:
Unlike hormonal peptides that act on membrane receptors, Epithalon operates at the genomic regulation level. Its focus on telomere biology differentiates it from endocrine modulators. This molecular positioning places it within high-level aging research rather than metabolic or anabolic categories. - Supports integrated longevity pathway investigation:
Aging is influenced by interconnected processes including telomere shortening, oxidative stress, and circadian disruption. Epithalon is studied as a multi-pathway modulator within this framework. Its role in telomere and pineal research integrates genomic and neuroendocrine perspectives in experimental aging models.
Research Data
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Pen Dosage Chart
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Included In The Box
Every product arrives in a premium, custom-designed PEPTIDE.Power box, engineered for convenience, hygiene, and safe storage in your refrigerator. Inside, you will find everything needed for your full research protocol:
- 1× Disposable Pre-Mixed Injection Pen
- Powered by our proprietary PSM Technology™ – precision stabilization & mixing system for consistent potency
- 10× Ultra-thin Needles (33G, 4 mm)
- 10× Alcohol Pads for sterile preparation
- Internal Stabilizing Foam Insert to prevent shaking during transport
- Instruction Panel printed on the inside of the box for quick reference
- Security Seal Sticker ensuring the package has not been opened or tampered with
Storage
Store the product in a refrigerator at 1 – 7°C immediately upon delivery. To maintain optimal stability, keep the pen away from light, and do not expose it to repeated temperature changes.
Once reconstituted (all our pens come pre-mixed), research compounds remain stable for 6 – 8 weeks under proper refrigeration.
Do not freeze after reconstitution. Always keep the box closed so the pen, needles, and alcohol pads stay clean and protected.
For best results, use the product consistently within the recommended time window and always follow your research protocol.
Delivery
We ship with Next-Day EU Delivery via DHL Express or UPS Express.
All orders are prepared fresh on the day of dispatch, placed in EPS cold-chain transport boxes, and shipped with cooling elements to maintain a stable temperature throughout the journey.
Our logistics process is designed so the package arrives overnight, avoiding customs delays inside the European Union.
Products are shipped from our EU facility, ensuring no import duties, no customs clearance, and always fast and secure delivery.
Payment
Due to the nature of research peptides and the high-risk category assigned by payment processors, credit card companies do not support merchants in this field.
For this reason, we accept bank transfers only.
Within the European Union, SEPA transfers are fast, low-cost, and usually arrive within minutes to a few hours, making the payment process smooth and simple.
Once the transfer is received, your order is prepared immediately and dispatched the same day (cut-off dependent).
This method ensures compliance, security, and continuity of service for all customers across the EU.
