SS-31
$94.80
SS-31 (Elamipretide) - Mitochondrial Protection & Cellular Energy
Description
SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide developed to support mitochondrial membrane stability and bioenergetic function in research settings. It belongs to a class of cell-penetrating peptides designed to localize within the inner mitochondrial membrane. SS-31 has been studied primarily in domains such as mitochondrial dysfunction, aging biology, cardiometabolic research, and neuromuscular models. In experimental systems, it has been observed to influence ATP production and reactive oxygen species balance.
Our formulation is provided in a stabilized pre-mixed injection pen for SubQ administration. Subcutaneous delivery supports consistent systemic exposure and high mitochondrial bioavailability in research protocols. Each unit is freshly prepared to preserve peptide integrity and ensure standardized dosing. This format eliminates multi-step vial preparation and supports simplified laboratory handling. The product is formulated strictly for research use only.
In research models, SS-31 has been observed to bind cardiolipin, a phospholipid unique to the inner mitochondrial membrane. This interaction appears to stabilize electron transport chain function → ↑ ATP synthesis efficiency and ↓ oxidative stress markers. Preclinical data show improved mitochondrial respiration and reduced mitochondrial swelling under stress conditions. Early human studies have explored its effects in mitochondrial-related dysfunction models.
Clinical Status
Human RCT ✔ | Observational ✔ | Animal ✔ | In vitro ✔
Evaluated in human clinical trials for mitochondrial and cardiovascular research indications.
Mechanism of Action
SS-31 works by targeting and stabilizing mitochondria, the energy-producing structures inside cells. In research models, it selectively binds to cardiolipin in the inner mitochondrial membrane. This stabilizes electron transport chain complexes → ↑ ATP production efficiency. Studies indicate ↓ mitochondrial reactive oxygen species (ROS) generation under stress conditions. These effects support improved cellular energy dynamics in experimental systems.
Benefits
- Mitochondrial Membrane Stabilization:
SS-31 has been studied for its selective binding to cardiolipin within the inner mitochondrial membrane. Research suggests this interaction stabilizes mitochondrial cristae structure. Improved membrane integrity supports optimized electron transport chain function. Preclinical studies indicate enhanced mitochondrial efficiency under stress conditions. These findings position SS-31 as a central peptide in mitochondrial biology research. - Enhanced ATP Production Efficiency:
In experimental models, SS-31 has been observed to improve oxidative phosphorylation dynamics. Studies demonstrate ↑ ATP synthesis efficiency through stabilization of respiratory chain complexes. This appears to support improved cellular energy availability. Animal research documents enhanced mitochondrial respiration rates. Evidence spans in vitro, animal, and early-stage human data. - Reduction Of Mitochondrial Oxidative Stress:
SS-31 has been associated with ↓ mitochondrial reactive oxygen species production in laboratory models. Reduced electron leak from the respiratory chain has been documented. This contributes to lower oxidative damage within mitochondria. Preclinical data show improved mitochondrial membrane potential under oxidative stress conditions. - Cardiometabolic Research Applications:
The peptide has been evaluated in cardiac and metabolic research contexts. Animal studies suggest improved mitochondrial function in cardiac tissue models. Enhanced myocardial bioenergetics has been documented. Early human trials have explored its effects in mitochondrial-related dysfunction studies. - Neuromuscular And Muscle Function Research:
SS-31 has been studied in skeletal muscle and neuromuscular models. Research indicates improved mitochondrial density and respiratory capacity in animal systems. Enhanced muscle bioenergetics has been observed under stress conditions. These findings remain within controlled research environments. - Electron Transport Chain Optimization:
By stabilizing cardiolipin, SS-31 supports optimal assembly of respiratory supercomplexes. This leads to improved electron flow → ↑ oxidative phosphorylation efficiency. Laboratory measurements demonstrate enhanced mitochondrial membrane potential. Evidence type: Animal ▣ | In vitro ▣. - Cellular Energy Resilience:
In models of metabolic stress, SS-31 has been observed to preserve mitochondrial function. Improved bioenergetic stability has been measured during oxidative challenge experiments. This regulatory effect supports cellular resilience in research contexts. - High Bioavailability Through Subcutaneous Administration:
Provided in a stabilized pre-mixed injection pen for SubQ administration, supporting consistent experimental dosing. Subcutaneous delivery enables reliable systemic exposure in research models. Each unit is prepared fresh and intended strictly for laboratory use.
Research Data
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Included In The Box
Every product arrives in a premium, custom-designed PEPTIDE.Power box, engineered for convenience, hygiene, and safe storage in your refrigerator. Inside, you will find everything needed for your full research protocol:
- 1× Disposable Pre-Mixed Injection Pen
- Powered by our proprietary PSM Technology™ – precision stabilization & mixing system for consistent potency
- 10× Ultra-thin Needles (33G, 4 mm)
- 10× Alcohol Pads for sterile preparation
- Internal Stabilizing Foam Insert to prevent shaking during transport
- Instruction Panel printed on the inside of the box for quick reference
- Security Seal Sticker ensuring the package has not been opened or tampered with
Storage
Store the product in a refrigerator at 1 – 7°C immediately upon delivery. To maintain optimal stability, keep the pen away from light, and do not expose it to repeated temperature changes.
Once reconstituted (all our pens come pre-mixed), research compounds remain stable for 6 – 8 weeks under proper refrigeration.
Do not freeze after reconstitution. Always keep the box closed so the pen, needles, and alcohol pads stay clean and protected.
For best results, use the product consistently within the recommended time window and always follow your research protocol.
Delivery
We ship with Next-Day EU Delivery via DHL Express or UPS Express.
All orders are prepared fresh on the day of dispatch, placed in EPS cold-chain transport boxes, and shipped with cooling elements to maintain a stable temperature throughout the journey.
Our logistics process is designed so the package arrives overnight, avoiding customs delays inside the European Union.
Products are shipped from our EU facility, ensuring no import duties, no customs clearance, and always fast and secure delivery.
Payment
Due to the nature of research peptides and the high-risk category assigned by payment processors, credit card companies do not support merchants in this field.
For this reason, we accept bank transfers only.
Within the European Union, SEPA transfers are fast, low-cost, and usually arrive within minutes to a few hours, making the payment process smooth and simple.
Once the transfer is received, your order is prepared immediately and dispatched the same day (cut-off dependent).
This method ensures compliance, security, and continuity of service for all customers across the EU.
