{"id":44011,"date":"2026-10-28T21:43:12","date_gmt":"2026-10-28T21:43:12","guid":{"rendered":"https:\/\/peptidepowereu.is\/?post_type=product&#038;p=44011"},"modified":"2026-10-28T21:44:21","modified_gmt":"2026-10-28T21:44:21","slug":"eloralintide","status":"publish","type":"product","link":"https:\/\/peptidepowereu.is\/ro\/eloralintide\/","title":{"rendered":"Eloralintide"},"content":{"rendered":"<p><strong>Eloralintide<\/strong> este un <strong>derivat de amilin\u0103 modificat cu 37 de reziduuri<\/strong> (C201H319N49O65S2, ~4526.1 g\/mol) dezvoltat sub codul LY3841136. Lan\u021bul s\u0103u con\u021bine reziduuri non-standard care \u00eei extind durata de ac\u021biune. \u00cen testele celulare a activat preferen\u021bial <strong>receptorul AMY1<\/strong> uman, de aproximativ 12 ori mai mult dec\u00e2t receptorul calcitoninei \u0219i de 11 ori mai mult dec\u00e2t receptorul AMY3.<\/p>\n<p>La \u0219obolanii obezi indu\u0219i prin diet\u0103, eloralintide a <strong>redus aportul alimentar<\/strong> \u0219i a <strong>sc\u0103zut greutatea corporal\u0103<\/strong> \u00eentr-o manier\u0103 dependent\u0103 de doz\u0103, \u00een principal prin <strong>pierderea masei grase<\/strong>, iar studiile farmacocinetice la \u0219obolani \u0219i maimu\u021be au ar\u0103tat o expunere cu ac\u021biune prelungit\u0103.<\/p>\n<p>\u00cen cercet\u0103rile publicate la om, eloralintide administrat subcutanat o dat\u0103 pe s\u0103pt\u0103m\u00e2n\u0103 a fost evaluat \u00een studii de faz\u0103 1 \u0219i \u00eentr-un studiu de faz\u0103 2 de 48 de s\u0103pt\u0103m\u00e2ni, controlat cu placebo, la adul\u021bi cu obezitate sau supraponderali, care a raportat modific\u0103ri medii ale greut\u0103\u021bii corporale \u00eentre -9% \u0219i -20% pe bra\u021bele de doz\u0103, fa\u021b\u0103 de -0,4% cu placebo. Grea\u021ba \u0219i oboseala au fost cele mai frecvent raportate evenimente adverse.<\/p>\n<p>Furnizat sub form\u0103 de <strong>pen de injec\u021bie pre-amestecat 10 mg \/ 1 mL<\/strong> pentru utilizare <strong>SubQ<\/strong> \u00een condi\u021bii de laborator; 1 clic elibereaz\u0103 0,1 mg.<\/p>\n<p><strong>Status Clinic:<\/strong><br \/>\nEloralintide este o <strong>peptid\u0103 de cercetare \u00een faz\u0103 investiga\u021bional\u0103<\/strong>. Nu este un agonist al receptorului GLP-1 \u0219i nu este aprobat pentru uz medical \u00een nicio \u021bar\u0103; r\u0103m\u00e2ne restric\u021bionat la <strong>cercetarea experimental\u0103 \u0219i de laborator<\/strong>.<\/p>\n<p><strong>Tip de dovezi:<\/strong><br \/>\nStudiu clinic \u2714 | Observa\u021bional \u2610 | Animal \u2714 | In vitro \u2714 | Reglementare \u2610<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Eloralintide este un derivat de amilin\u0103 modificat cu 37 de reziduuri (C201H319N49O65S2, ~4526.1 g\/mol) dezvoltat sub codul LY3841136. Lan\u021bul s\u0103u con\u021bine reziduuri non-standard care \u00eei extind durata de ac\u021biune. \u00cen testele celulare a activat preferen\u021bial receptorul AMY1 uman, de aproximativ 12 ori mai mult dec\u00e2t receptorul calcitoninei \u0219i de 11 ori mai mult dec\u00e2t receptorul [&hellip;]<\/p>\n","protected":false},"featured_media":44025,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[341,340],"product_tag":[],"class_list":["post-44011","product","type-product","status-publish","has-post-thumbnail","product_cat-anti-aging-longevity-research","product_cat-weight-loss-metabolic-optimization-research","first","instock","shipping-taxable","purchasable","product-type-variable"],"acf":[],"_links":{"self":[{"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/product\/44011","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/media\/44025"}],"wp:attachment":[{"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/media?parent=44011"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/product_brand?post=44011"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/product_cat?post=44011"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/peptidepowereu.is\/ro\/wp-json\/wp\/v2\/product_tag?post=44011"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}