{"id":39142,"date":"2026-06-21T10:23:13","date_gmt":"2026-06-21T10:23:13","guid":{"rendered":"https:\/\/peptidepowereu.is\/?post_type=product&#038;p=39142"},"modified":"2026-06-21T11:03:46","modified_gmt":"2026-06-21T11:03:46","slug":"humanin","status":"publish","type":"product","link":"https:\/\/peptidepowereu.is\/el\/humanin\/","title":{"rendered":"Humanin"},"content":{"rendered":"<p><strong>Humanin<\/strong> is a <strong>24-amino-acid mitochondrial-derived peptide (MDP)<\/strong> encoded within the <strong>16S ribosomal RNA gene of mitochondrial DNA<\/strong>. It is studied for its <strong>cytoprotective<\/strong>, <strong>anti-apoptotic<\/strong>, and <strong>metabolic-modulating properties<\/strong> across neuronal, cardiovascular, and endocrine research models.<\/p>\n<p>In experimental settings, Humanin has been observed to <strong>inhibit Bax-mediated apoptosis<\/strong>, suppress mitochondrial cytochrome c release, and protect cells from <strong>oxidative stress<\/strong> and <strong>amyloid-beta toxicity<\/strong>. It is reported to interact with the <strong>FPR2 and CNTFR\/WSX-1\/gp130 receptor complexes<\/strong>, activating downstream <strong>STAT3<\/strong> and <strong>ERK signaling pathways<\/strong> linked to cellular survival.<\/p>\n<p>Additional research highlights Humanin&#8217;s role in <strong>insulin sensitization<\/strong>, <strong>lipid metabolism<\/strong>, and <strong>neuroprotection<\/strong>, particularly in models of Alzheimer&#8217;s disease, ischemic injury, and age-related metabolic decline. Declining endogenous Humanin levels with age have made it a focus of <strong>longevity and mitochondrial communication research<\/strong>.<\/p>\n<p>Supplied as a <strong>lyophilized powder<\/strong> requiring reconstitution with bacteriostatic water, Humanin is intended for <strong>subcutaneous research administration<\/strong> under controlled laboratory conditions.<\/p>\n<p><strong>Clinical Status:<\/strong><br \/>\nHumanin is a <strong>research peptide<\/strong> evaluated extensively in animal models and in vitro systems for neuroprotection, metabolic regulation, and apoptosis modulation. It is not approved for medical use and remains restricted to <strong>experimental and laboratory research<\/strong>.<\/p>\n<p><strong>Evidence type:<\/strong><br \/>\nHuman RCT \u2610 | Observational \u2714 | Animal \u2714 | In vitro \u2714 | Regulatory \u2610<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Humanin is a 24-amino-acid mitochondrial-derived peptide (MDP) encoded within the 16S ribosomal RNA gene of mitochondrial DNA. It is studied<\/p>\n","protected":false},"featured_media":39524,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[506,497],"product_tag":[],"class_list":["post-39142","product","type-product","status-publish","has-post-thumbnail","product_cat-mitochondrial-health-cellular-energy-research","product_cat-anti-aging-longevity-research","first","instock","shipping-taxable","purchasable","product-type-variable"],"acf":[],"_links":{"self":[{"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/product\/39142","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/types\/product"}],"version-history":[{"count":1,"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/product\/39142\/revisions"}],"predecessor-version":[{"id":39525,"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/product\/39142\/revisions\/39525"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/media\/39524"}],"wp:attachment":[{"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/media?parent=39142"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/product_brand?post=39142"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/product_cat?post=39142"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/peptidepowereu.is\/el\/wp-json\/wp\/v2\/product_tag?post=39142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}